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Zoë Soon

Learning Objectives

By the end of this section, you will be able to:

  • Describe the body’s surface membranes and barriers that defend against pathogens including the body’s physical and chemical mechanisms of defense.
  • Describe innate defenses that involve diapedesis, chemotaxis, opsonization, and membrane attack complexes.
  • List the phagocytic cells involved in innate defense and explain the steps involved in phagocytosis.
  • Describe the role of natural killer cells as well as their mode of action.
  • Explain how complement proteins and interferon cytokines function during innate defense.
  • Discuss the role of pattern-recognition receptors in innate defenses.
  • List the steps of the inflammatory response, detailing both the cells and chemicals involved.
  • Explain the cause of the four cardinal signs of inflammation and why inflammation can be beneficial.
  • Describe different types of pyrogens.
  • Explain how fever occurs and why fever can be beneficial.

The major organs of the

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Pathology Copyright © 2022 by Jennifer Kong and Helen Dyck is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, except where otherwise noted.

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