{"id":678,"date":"2023-12-04T10:27:44","date_gmt":"2023-12-04T15:27:44","guid":{"rendered":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/chapter\/adaptive-specific-immunity\/"},"modified":"2023-12-04T10:27:44","modified_gmt":"2023-12-04T15:27:44","slug":"adaptive-specific-immunity","status":"publish","type":"chapter","link":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/chapter\/adaptive-specific-immunity\/","title":{"raw":"Adaptive (Specific) Immunity","rendered":"Adaptive (Specific) Immunity"},"content":{"raw":"\n
\n
\n

Learning Objectives<\/p>\n\n<\/header>\n

\n\nBy the end of this section, you will be able to:\n
    \n \t
  • Compare and contrast antibody-mediated (humoral) and cell-mediated immunity<\/span><\/li>\n \t
  • Describe the immunological memory (anamnestic) response.<\/span><\/li>\n \t
  • Distinguish among the various types of lymphocytes, including helper T cells, cytotoxic T cells, regulatory (or suppressor) T cells, B cells, plasma cells, and memory cells.<\/li>\n \t
  • With respect to B cells and T cells:<\/li>\n \t
  • Define immunocompetence and self tolerance and distinguish between naive and activated immune cells.<\/li>\n \t
  • Compare & contrast the sites where the cells originate and achieve their immunocompetence, and the primary location of the immunocompetent cells in the body.<\/li>\n \t
  • Compare & contrast the mechanisms of antigen challenge and the clonal selection processes, including effector cells, helper cells, memory cells, and important cytokines.<\/li>\n \t
  • Describe the contribution of clonal deletion to immunity.<\/li>\n \t
  • Explain how activation of Cytotoxic T lymphocytes occurs.<\/li>\n \t
  • Explain how activation of B lymphocytes occurs.<\/li>\n \t
  • Explain the role of Class I and Class II Major Histocompatibility Complexes (MHC) in T and B lymphocyte activation, discussing the role of Antigen-Presenting Cells (APCs).<\/li>\n \t
  • Describe mechanisms of antibody action.<\/li>\n \t
  • Compare and contrast the five classes of antibodies in terms of structural and functional features in addition to location.<\/li>\n \t
  • Explain in graph format the primary and secondary immune response, in terms of the relative concentrations of different classes of antibodies and lymphocytes produced over time.<\/li>\n<\/ul>\n<\/div>\n<\/div>\nThe major organs of the\n\n<\/div>\n","rendered":"
    \n
    \n
    \n

    Learning Objectives<\/p>\n<\/header>\n

    \n

    By the end of this section, you will be able to:<\/p>\n

      \n
    • Compare and contrast antibody-mediated (humoral) and cell-mediated immunity<\/span><\/li>\n
    • Describe the immunological memory (anamnestic) response.<\/span><\/li>\n
    • Distinguish among the various types of lymphocytes, including helper T cells, cytotoxic T cells, regulatory (or suppressor) T cells, B cells, plasma cells, and memory cells.<\/li>\n
    • With respect to B cells and T cells:<\/li>\n
    • Define immunocompetence and self tolerance and distinguish between naive and activated immune cells.<\/li>\n
    • Compare & contrast the sites where the cells originate and achieve their immunocompetence, and the primary location of the immunocompetent cells in the body.<\/li>\n
    • Compare & contrast the mechanisms of antigen challenge and the clonal selection processes, including effector cells, helper cells, memory cells, and important cytokines.<\/li>\n
    • Describe the contribution of clonal deletion to immunity.<\/li>\n
    • Explain how activation of Cytotoxic T lymphocytes occurs.<\/li>\n
    • Explain how activation of B lymphocytes occurs.<\/li>\n
    • Explain the role of Class I and Class II Major Histocompatibility Complexes (MHC) in T and B lymphocyte activation, discussing the role of Antigen-Presenting Cells (APCs).<\/li>\n
    • Describe mechanisms of antibody action.<\/li>\n
    • Compare and contrast the five classes of antibodies in terms of structural and functional features in addition to location.<\/li>\n
    • Explain in graph format the primary and secondary immune response, in terms of the relative concentrations of different classes of antibodies and lymphocytes produced over time.<\/li>\n<\/ul>\n<\/div>\n<\/div>\n

      The major organs of the<\/p>\n<\/div>\n","protected":false},"author":103,"menu_order":7,"template":"","meta":{"pb_show_title":"","pb_short_title":"","pb_subtitle":"","pb_authors":["zoe-soon"],"pb_section_license":""},"chapter-type":[],"contributor":[183],"license":[],"class_list":["post-678","chapter","type-chapter","status-publish","hentry","contributor-zoe-soon"],"part":649,"_links":{"self":[{"href":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/wp-json\/pressbooks\/v2\/chapters\/678","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/wp-json\/wp\/v2\/users\/103"}],"version-history":[{"count":0,"href":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/wp-json\/pressbooks\/v2\/chapters\/678\/revisions"}],"part":[{"href":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/wp-json\/pressbooks\/v2\/parts\/649"}],"metadata":[{"href":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/wp-json\/pressbooks\/v2\/chapters\/678\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/wp-json\/wp\/v2\/media?parent=678"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/wp-json\/pressbooks\/v2\/chapter-type?post=678"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/wp-json\/wp\/v2\/contributor?post=678"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/dcbiol2200\/wp-json\/wp\/v2\/license?post=678"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}