{"id":122,"date":"2019-09-22T17:54:40","date_gmt":"2019-09-22T21:54:40","guid":{"rendered":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/chapter\/3-16-anitmalarials\/"},"modified":"2022-03-16T12:54:20","modified_gmt":"2022-03-16T16:54:20","slug":"3-16-anitmalarials","status":"publish","type":"chapter","link":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/chapter\/3-16-anitmalarials\/","title":{"raw":"3.17 Antimalarials","rendered":"3.17 Antimalarials"},"content":{"raw":"Malaria is a prevalent protozoal disease impacting individuals across the world. According to the Centers for Disease Control, approximately 450 cases of malaria are diagnosed in Canada each year.[footnote]Malaria. (2016). Surveillance of Malaria. https:\/\/www.canada.ca\/en\/public-health\/services\/diseases\/malaria\/surveillance-malaria.html#shr-pg0<\/a>[\/footnote]\r\n\r\nIndications for Use:<\/strong> Antimalarials are used for the prevention or treatment of malaria.\r\n\r\nMechanism of Action:<\/strong> Antimalarial agents work by targeting specific intracellular processes that impact cell development.[footnote]Achieng, A., Rawat, M., Ogutu, B., Guyah, B., Ong'echa, J.M., Perkins, D., & Kempaiah, P. (2017). Antimalarials: Molecular drug targets and mechanism of action. Current Topics in Medicinal Chemistry, 17<\/em>, 1-15. [\/footnote]<\/sup>\r\n\r\nNursing Considerations across the Lifespan:<\/strong> Antimalarial agents are safe to use for all age groups.\u00a0 Dose adjustments are not needed for renal or liver dysfunction.\r\n\r\nSpecial Administration Considerations:<\/strong> Antimalarial medications may impact hearing and vision so clients should be monitored carefully for adverse effects. Additionally, antimalarial medications may cause GI upset, so clients should be instructed to take these medications with food.\r\n\r\nClient Teaching & Education: <\/strong>Clients should receive instruction to take medication as prescribed and adhere to the full prescription regimen.\u00a0 Clients should minimize additional exposure to mosquitoes using preventative means such as repellents, protective clothing, netting, etc.\u00a0 Clients on chloroquine therapy should also avoid alcohol.\u00a0 Chloroquine can be extremely toxic to children and should be safely stored and out of reach.\u00a0 Clients receiving antimalarial therapy may have increased sensitivity to light and should be counseled to wear protective glasses to prevent ocular damage.\u00a0 Treatment often requires sustained regimens of six months or greater so clients should be monitored carefully for adherence and compliance.[footnote]uCentral from Unbound Medicine. https:\/\/www.unboundmedicine.com\/ucentral<\/a>[\/footnote]<\/sup>\r\n\r\nNow let's take a closer look at the medication card on chloroquine in Table 3.16.[footnote]Daily Med, https:\/\/dailymed.nlm.nih.gov\/dailymed\/index.cfm<\/a>, used for hyperlinked medications in this module. Retrieved June 27, 2019[\/footnote]<\/sup>[footnote]UpToDate (2021). Chloroquine<\/em>. https:\/\/www.uptodate.com\/contents\/search<\/a>[\/footnote]\r\n\r\nTable 3.16 Chloroquine Medication Card\r\n\r\n\"Antimalarials\r\n
\r\n

Clinical Reasoning and Decision-Making Activity 3.16a<\/strong><\/h2>\r\n<\/header>\r\n
\r\n\r\nUsing the above information, consider the following clinical scenario question:<\/strong>\r\n\r\nA nurse is providing medication teaching to a client who is planning on visiting a country with high rates of malaria to do mission work. The client states, \"I'm glad I only have to take this medication for a week. The side effects sound horrific!\" What is the nurse's best response regarding the length of therapy?\r\n\r\nNote: Answers to the activities can be found in the \"Answer Key<\/a>\" sections at the end of the book.\r\n\r\n<\/div>\r\n<\/div>\r\n ","rendered":"

Malaria is a prevalent protozoal disease impacting individuals across the world. According to the Centers for Disease Control, approximately 450 cases of malaria are diagnosed in Canada each year.[1]<\/sup><\/a><\/p>\n

Indications for Use:<\/strong> Antimalarials are used for the prevention or treatment of malaria.<\/p>\n

Mechanism of Action:<\/strong> Antimalarial agents work by targeting specific intracellular processes that impact cell development.[2]<\/sup><\/a><\/sup><\/p>\n

Nursing Considerations across the Lifespan:<\/strong> Antimalarial agents are safe to use for all age groups.\u00a0 Dose adjustments are not needed for renal or liver dysfunction.<\/p>\n

Special Administration Considerations:<\/strong> Antimalarial medications may impact hearing and vision so clients should be monitored carefully for adverse effects. Additionally, antimalarial medications may cause GI upset, so clients should be instructed to take these medications with food.<\/p>\n

Client Teaching & Education: <\/strong>Clients should receive instruction to take medication as prescribed and adhere to the full prescription regimen.\u00a0 Clients should minimize additional exposure to mosquitoes using preventative means such as repellents, protective clothing, netting, etc.\u00a0 Clients on chloroquine therapy should also avoid alcohol.\u00a0 Chloroquine can be extremely toxic to children and should be safely stored and out of reach.\u00a0 Clients receiving antimalarial therapy may have increased sensitivity to light and should be counseled to wear protective glasses to prevent ocular damage.\u00a0 Treatment often requires sustained regimens of six months or greater so clients should be monitored carefully for adherence and compliance.[3]<\/sup><\/a><\/sup><\/p>\n

Now let’s take a closer look at the medication card on chloroquine in Table 3.16.[4]<\/sup><\/a><\/sup>[5]<\/sup><\/a><\/p>\n

Table 3.16 Chloroquine Medication Card<\/p>\n

\"Antimalarials<\/p>\n

\n
\n

Clinical Reasoning and Decision-Making Activity 3.16a<\/strong><\/h2>\n<\/header>\n
\n

Using the above information, consider the following clinical scenario question:<\/strong><\/p>\n

A nurse is providing medication teaching to a client who is planning on visiting a country with high rates of malaria to do mission work. The client states, “I’m glad I only have to take this medication for a week. The side effects sound horrific!” What is the nurse’s best response regarding the length of therapy?<\/p>\n

Note: Answers to the activities can be found in the “Answer Key<\/a>” sections at the end of the book.<\/p>\n<\/div>\n<\/div>\n

 <\/p>\n

Media Attributions<\/h2>