{"id":168,"date":"2019-10-17T22:19:06","date_gmt":"2019-10-18T02:19:06","guid":{"rendered":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/chapter\/4-11-beta-1-agonist\/"},"modified":"2022-03-16T13:03:24","modified_gmt":"2022-03-16T17:03:24","slug":"4-12-beta-1-agonist","status":"publish","type":"chapter","link":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/chapter\/4-12-beta-1-agonist\/","title":{"raw":"4.12 Beta-1 Agonists","rendered":"4.12 Beta-1 Agonists"},"content":{"raw":"Dobutamine is a Beta-1 agonist.\r\n\r\n<strong>Mechanism of Action:<\/strong>\u00a0 Dobutamine stimulates Beta-1 receptors to increase heart rate, force of contraction, and conduction velocity.\r\n\r\n<strong>Indications for Use:<\/strong> Dobutamine is used to treat cardiogenic shock and severe heart failure to increase contractility and cardiac output.\r\n\r\n<strong>Nursing Considerations Across the Lifespan:<\/strong> Beta-1 agonists can safely be administered to pediatric clients, but doses must be adjusted according to weight. These medications are also safe in the older adult population, with no special dose adjustments for renal or liver insufficiency. Beta-1 agonists should not be given in pregnancy, if they can be avoided.\r\n\r\nIn IV administration, dilute concentration before administering. Continuously monitor electrocardiogram (ECG), blood pressure, cardiac output, and urine output during therapy. This drug can cause a marked increase in heart rate and blood pressure. Report all adverse reactions promptly, especially laboured breathing, angina, palpitations, and dizziness.\r\n\r\n<strong>Patient Teaching &amp; Education: <\/strong>The client should be instructed to inform the nurse immediately if they notice chest pain, shortness of breath, or numbness or tingling in the extremities.<sup>[footnote]uCentral from Unbound Medicine. <a href=\"https:\/\/www.unboundmedicine.com\/ucentral\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.unboundmedicine.com\/ucentral<\/a>[\/footnote]<\/sup>\r\n\r\nNow let's take a closer look at the dobutamine medication grid in Table 4.12.<sup>[footnote]This work is a derivative of <a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/\" target=\"_blank\" rel=\"noopener noreferrer\">Daily Med<\/a> by <a href=\"https:\/\/www.nlm.nih.gov\/\" target=\"_blank\" rel=\"noopener noreferrer\">U.S. National Library of Medicine<\/a> in the <a href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/\" target=\"_blank\" rel=\"noopener noreferrer\">public domain<\/a>.[\/footnote]<\/sup>[footnote]UpToDate (2021). <em>Dobutamine<\/em>. <a href=\"https:\/\/www.uptodate.com\/contents\/search\">https:\/\/www.uptodate.com\/contents\/search<\/a>[\/footnote] Because information about medication is constantly changing, nurses should always consult evidence-based resources to review current recommendations before administering specific medication.\r\n\r\nTable 4.12 <a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=6b17b98b-e06d-42ed-925f-69aa2699dead&amp;audience=consumer\">Dobutamine<\/a> Medication Card\r\n\r\n<img class=\"aligncenter wp-image-2001 size-full\" src=\"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/10\/4-dobutamine-scaled.jpg\" alt=\"Beta-1 Agonist drug card\" width=\"2560\" height=\"770\" \/>\r\n\r\n&nbsp;","rendered":"<p>Dobutamine is a Beta-1 agonist.<\/p>\n<p><strong>Mechanism of Action:<\/strong>\u00a0 Dobutamine stimulates Beta-1 receptors to increase heart rate, force of contraction, and conduction velocity.<\/p>\n<p><strong>Indications for Use:<\/strong> Dobutamine is used to treat cardiogenic shock and severe heart failure to increase contractility and cardiac output.<\/p>\n<p><strong>Nursing Considerations Across the Lifespan:<\/strong> Beta-1 agonists can safely be administered to pediatric clients, but doses must be adjusted according to weight. These medications are also safe in the older adult population, with no special dose adjustments for renal or liver insufficiency. Beta-1 agonists should not be given in pregnancy, if they can be avoided.<\/p>\n<p>In IV administration, dilute concentration before administering. Continuously monitor electrocardiogram (ECG), blood pressure, cardiac output, and urine output during therapy. This drug can cause a marked increase in heart rate and blood pressure. Report all adverse reactions promptly, especially laboured breathing, angina, palpitations, and dizziness.<\/p>\n<p><strong>Patient Teaching &amp; Education: <\/strong>The client should be instructed to inform the nurse immediately if they notice chest pain, shortness of breath, or numbness or tingling in the extremities.<sup><a class=\"footnote\" title=\"uCentral from Unbound Medicine. https:\/\/www.unboundmedicine.com\/ucentral\" id=\"return-footnote-168-1\" href=\"#footnote-168-1\" aria-label=\"Footnote 1\"><sup class=\"footnote\">[1]<\/sup><\/a><\/sup><\/p>\n<p>Now let&#8217;s take a closer look at the dobutamine medication grid in Table 4.12.<sup><a class=\"footnote\" title=\"This work is a derivative of Daily Med by U.S. National Library of Medicine in the public domain.\" id=\"return-footnote-168-2\" href=\"#footnote-168-2\" aria-label=\"Footnote 2\"><sup class=\"footnote\">[2]<\/sup><\/a><\/sup><a class=\"footnote\" title=\"UpToDate (2021). Dobutamine. https:\/\/www.uptodate.com\/contents\/search\" id=\"return-footnote-168-3\" href=\"#footnote-168-3\" aria-label=\"Footnote 3\"><sup class=\"footnote\">[3]<\/sup><\/a> Because information about medication is constantly changing, nurses should always consult evidence-based resources to review current recommendations before administering specific medication.<\/p>\n<p>Table 4.12 <a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=6b17b98b-e06d-42ed-925f-69aa2699dead&amp;audience=consumer\">Dobutamine<\/a> Medication Card<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-2001 size-full\" src=\"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/10\/4-dobutamine-scaled.jpg\" alt=\"Beta-1 Agonist drug card\" width=\"2560\" height=\"770\" srcset=\"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/10\/4-dobutamine-scaled.jpg 2560w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/10\/4-dobutamine-300x90.jpg 300w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/10\/4-dobutamine-1024x308.jpg 1024w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/10\/4-dobutamine-768x231.jpg 768w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/10\/4-dobutamine-1536x462.jpg 1536w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/10\/4-dobutamine-2048x616.jpg 2048w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/10\/4-dobutamine-65x20.jpg 65w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/10\/4-dobutamine-225x68.jpg 225w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/10\/4-dobutamine-350x105.jpg 350w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><\/p>\n<p>&nbsp;<\/p>\n<div class=\"media-attributions clear\" prefix:cc=\"http:\/\/creativecommons.org\/ns#\" prefix:dc=\"http:\/\/purl.org\/dc\/terms\/\"><h2>Media Attributions<\/h2><ul><li >4-dobutamine       <\/li><\/ul><\/div><hr class=\"before-footnotes clear\" \/><div class=\"footnotes\"><ol><li id=\"footnote-168-1\">uCentral from Unbound Medicine. <a href=\"https:\/\/www.unboundmedicine.com\/ucentral\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.unboundmedicine.com\/ucentral<\/a> <a href=\"#return-footnote-168-1\" class=\"return-footnote\" aria-label=\"Return to footnote 1\">&crarr;<\/a><\/li><li id=\"footnote-168-2\">This work is a derivative of <a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/\" target=\"_blank\" rel=\"noopener noreferrer\">Daily Med<\/a> by <a href=\"https:\/\/www.nlm.nih.gov\/\" target=\"_blank\" rel=\"noopener noreferrer\">U.S. National Library of Medicine<\/a> in the <a href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/\" target=\"_blank\" rel=\"noopener noreferrer\">public domain<\/a>. <a href=\"#return-footnote-168-2\" class=\"return-footnote\" aria-label=\"Return to footnote 2\">&crarr;<\/a><\/li><li id=\"footnote-168-3\">UpToDate (2021). <em>Dobutamine<\/em>. <a href=\"https:\/\/www.uptodate.com\/contents\/search\">https:\/\/www.uptodate.com\/contents\/search<\/a> <a href=\"#return-footnote-168-3\" class=\"return-footnote\" aria-label=\"Return to footnote 3\">&crarr;<\/a><\/li><\/ol><\/div>","protected":false},"author":103,"menu_order":12,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":["open-resources-for-nursing-open-rn"],"pb_section_license":""},"chapter-type":[48],"contributor":[68],"license":[],"class_list":["post-168","chapter","type-chapter","status-publish","hentry","chapter-type-numberless","contributor-open-resources-for-nursing-open-rn"],"part":138,"_links":{"self":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/168","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/users\/103"}],"version-history":[{"count":8,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/168\/revisions"}],"predecessor-version":[{"id":2623,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/168\/revisions\/2623"}],"part":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/parts\/138"}],"metadata":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/168\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/media?parent=168"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapter-type?post=168"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/contributor?post=168"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/license?post=168"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}