{"id":225,"date":"2019-11-14T21:00:37","date_gmt":"2019-11-15T02:00:37","guid":{"rendered":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/chapter\/5-13-leukotriene-receptor-antagonists\/"},"modified":"2022-01-21T18:33:34","modified_gmt":"2022-01-21T23:33:34","slug":"5-13-leukotriene-receptor-antagonists","status":"publish","type":"chapter","link":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/chapter\/5-13-leukotriene-receptor-antagonists\/","title":{"raw":"5.13 Leukotriene Receptor Antagonists","rendered":"5.13 Leukotriene Receptor Antagonists"},"content":{"raw":"<h3>Leukotriene Receptor Antagonists<\/h3>\r\nMontelukast is a leukotriene antagonist medication with a distinctly shaped tablet. See Figure 5.13.<sup>[footnote]\"<a href=\"https:\/\/www.flickr.com\/photos\/neofedex\/3446761945\/\" target=\"_blank\" rel=\"noopener noreferrer\">Singulair 10mg<\/a>\" by <a href=\"https:\/\/www.flickr.com\/photos\/neofedex\/\" target=\"_blank\" rel=\"noopener noreferrer\">FedEx<\/a> is licenced under <a href=\"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/2.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">CC BY-NC-ND 2.0<\/a>[\/footnote]<\/sup>\r\n\r\n<strong>Mechanism of Action<\/strong>\r\n\r\nMontelukast blocks leukotriene receptors and decreases inflammation.\r\n\r\n<strong>Indications for Use<\/strong>\r\n\r\nMontelukast is used for the long-term control of asthma and for decreasing the frequency of asthma attacks.\u00a0 It is also indicated for exercise-induced bronchospasm and allergic rhinitis.\r\n\r\n<strong>Nursing Considerations Across the Lifespan<\/strong>\r\n\r\nThe medication is safe for children 12 months and older. It is available in granule packets and chewable tablets, as well as regular tablets.\r\n\r\n<strong>Adverse\/Side Effects<\/strong>\r\n\r\nMontelukast can cause headache, cough, nasal congestion, nausea, and hepatotoxicity.<sup>[footnote]Frandsen, G. &amp; Pennington, S. (2018). <em>Abrams\u2019 clinical drug: Rationales for nursing practice <\/em>(11th ed.). Wolters Kluwer.[\/footnote]<\/sup>\r\n\r\n[caption id=\"attachment_224\" align=\"aligncenter\" width=\"433\"]<img class=\"wp-image-224 size-full\" title=\"&quot;Singulair 10mg&quot; by FedEx is licenced under CC BY-NC-ND 2.0\" src=\"https:\/\/pressbooks.bccampus.ca\/knowinghome\/wp-content\/uploads\/sites\/1167\/2019\/11\/image9-6.png\" alt=\"Photo of Singular brand montelukast tablets\" width=\"433\" height=\"116\" \/> Figure 5.13 Montelukast Tablets[\/caption]\r\n\r\n<strong>Client Teaching &amp; Education<\/strong>\r\n\r\nClients should be instructed to take medications at the same time each day and at least two hours prior to exercise.\u00a0 They should not discontinue medications without notifying the healthcare provider.<sup>[footnote]uCentral from Unbound Medicine. <a href=\"https:\/\/www.unboundmedicine.com\/ucentral\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.unboundmedicine.com\/ucentral<\/a>[\/footnote]<\/sup>\r\n\r\nNow let's take a closer look at the medication card on montelukast in Table 5.13.<sup>[footnote]This work is a derivative of <a href=\"https:\/\/www.oercommons.org\/authoring\/54330-pharmacology-notes-nursing-implications-for-clinic\/view\" target=\"_blank\" rel=\"noopener noreferrer\">Pharmacology Notes: Nursing Implications for Clinical Practice<\/a> by <a href=\"https:\/\/www.oercommons.org\/profile\/213497\" target=\"_blank\" rel=\"noopener noreferrer\">Gloria Velarde<\/a> licensed under <a href=\"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">CC BY-NC-SA 4.0<\/a>.[\/footnote],[footnote]Frandsen, G. &amp; Pennington, S. (2018). <em>Abrams\u2019 clinical drug: Rationales for nursing practice <\/em>(11th ed.). Wolters Kluwer.[\/footnote], [footnote]This work is a derivative of <a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/\" target=\"_blank\" rel=\"noopener noreferrer\">Daily Med<\/a> by <a href=\"https:\/\/www.nlm.nih.gov\/\" target=\"_blank\" rel=\"noopener noreferrer\">U.S. National Library of Medicine<\/a> in the <a href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/\" target=\"_blank\" rel=\"noopener noreferrer\">public domain<\/a>. [\/footnote],[footnote]Adams, M., Holland, N., &amp; Urban, C. (2020). <em>Pharmacology for nurses: A pathophysiologic approach <\/em>(6th ed.)<em>.<\/em> pp. 622-63 &amp; 626. Pearson. [\/footnote]<\/sup>\r\n\r\nTable 5.13 Montelukast Medication Card\r\n\r\n<img class=\"alignnone size-full wp-image-1637\" src=\"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/LRA.jpg\" alt=\"\" width=\"1700\" height=\"2200\" \/>\r\n\r\n&nbsp;","rendered":"<h3>Leukotriene Receptor Antagonists<\/h3>\n<p>Montelukast is a leukotriene antagonist medication with a distinctly shaped tablet. See Figure 5.13.<sup><a class=\"footnote\" title=\"&quot;Singulair 10mg&quot; by FedEx is licenced under CC BY-NC-ND 2.0\" id=\"return-footnote-225-1\" href=\"#footnote-225-1\" aria-label=\"Footnote 1\"><sup class=\"footnote\">[1]<\/sup><\/a><\/sup><\/p>\n<p><strong>Mechanism of Action<\/strong><\/p>\n<p>Montelukast blocks leukotriene receptors and decreases inflammation.<\/p>\n<p><strong>Indications for Use<\/strong><\/p>\n<p>Montelukast is used for the long-term control of asthma and for decreasing the frequency of asthma attacks.\u00a0 It is also indicated for exercise-induced bronchospasm and allergic rhinitis.<\/p>\n<p><strong>Nursing Considerations Across the Lifespan<\/strong><\/p>\n<p>The medication is safe for children 12 months and older. It is available in granule packets and chewable tablets, as well as regular tablets.<\/p>\n<p><strong>Adverse\/Side Effects<\/strong><\/p>\n<p>Montelukast can cause headache, cough, nasal congestion, nausea, and hepatotoxicity.<sup><a class=\"footnote\" title=\"Frandsen, G. &amp; Pennington, S. (2018). Abrams\u2019 clinical drug: Rationales for nursing practice (11th ed.). Wolters Kluwer.\" id=\"return-footnote-225-2\" href=\"#footnote-225-2\" aria-label=\"Footnote 2\"><sup class=\"footnote\">[2]<\/sup><\/a><\/sup><\/p>\n<figure id=\"attachment_224\" aria-describedby=\"caption-attachment-224\" style=\"width: 433px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-224 size-full\" title=\"&quot;Singulair 10mg&quot; by FedEx is licenced under CC BY-NC-ND 2.0\" src=\"https:\/\/pressbooks.bccampus.ca\/knowinghome\/wp-content\/uploads\/sites\/1167\/2019\/11\/image9-6.png\" alt=\"Photo of Singular brand montelukast tablets\" width=\"433\" height=\"116\" srcset=\"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/image9-6.png 433w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/image9-6-300x80.png 300w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/image9-6-65x17.png 65w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/image9-6-225x60.png 225w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/image9-6-350x94.png 350w\" sizes=\"auto, (max-width: 433px) 100vw, 433px\" \/><figcaption id=\"caption-attachment-224\" class=\"wp-caption-text\">Figure 5.13 Montelukast Tablets<\/figcaption><\/figure>\n<p><strong>Client Teaching &amp; Education<\/strong><\/p>\n<p>Clients should be instructed to take medications at the same time each day and at least two hours prior to exercise.\u00a0 They should not discontinue medications without notifying the healthcare provider.<sup><a class=\"footnote\" title=\"uCentral from Unbound Medicine. https:\/\/www.unboundmedicine.com\/ucentral\" id=\"return-footnote-225-3\" href=\"#footnote-225-3\" aria-label=\"Footnote 3\"><sup class=\"footnote\">[3]<\/sup><\/a><\/sup><\/p>\n<p>Now let&#8217;s take a closer look at the medication card on montelukast in Table 5.13.<sup><a class=\"footnote\" title=\"This work is a derivative of Pharmacology Notes: Nursing Implications for Clinical Practice by Gloria Velarde licensed under CC BY-NC-SA 4.0.\" id=\"return-footnote-225-4\" href=\"#footnote-225-4\" aria-label=\"Footnote 4\"><sup class=\"footnote\">[4]<\/sup><\/a>,<a class=\"footnote\" title=\"Frandsen, G. &amp; Pennington, S. (2018). Abrams\u2019 clinical drug: Rationales for nursing practice (11th ed.). Wolters Kluwer.\" id=\"return-footnote-225-5\" href=\"#footnote-225-5\" aria-label=\"Footnote 5\"><sup class=\"footnote\">[5]<\/sup><\/a>, <a class=\"footnote\" title=\"This work is a derivative of Daily Med by U.S. National Library of Medicine in the public domain.\" id=\"return-footnote-225-6\" href=\"#footnote-225-6\" aria-label=\"Footnote 6\"><sup class=\"footnote\">[6]<\/sup><\/a>,<a class=\"footnote\" title=\"Adams, M., Holland, N., &amp; Urban, C. (2020). Pharmacology for nurses: A pathophysiologic approach (6th ed.). pp. 622-63 &amp; 626. Pearson.\" id=\"return-footnote-225-7\" href=\"#footnote-225-7\" aria-label=\"Footnote 7\"><sup class=\"footnote\">[7]<\/sup><\/a><\/sup><\/p>\n<p>Table 5.13 Montelukast Medication Card<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-1637\" src=\"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/LRA.jpg\" alt=\"\" width=\"1700\" height=\"2200\" srcset=\"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/LRA.jpg 1700w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/LRA-232x300.jpg 232w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/LRA-791x1024.jpg 791w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/LRA-768x994.jpg 768w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/LRA-1187x1536.jpg 1187w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/LRA-1583x2048.jpg 1583w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/LRA-65x84.jpg 65w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/LRA-225x291.jpg 225w, https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/1167\/2019\/11\/LRA-350x453.jpg 350w\" sizes=\"auto, (max-width: 1700px) 100vw, 1700px\" \/><\/p>\n<p>&nbsp;<\/p>\n<div class=\"media-attributions clear\" prefix:cc=\"http:\/\/creativecommons.org\/ns#\" prefix:dc=\"http:\/\/purl.org\/dc\/terms\/\"><h2>Media Attributions<\/h2><ul><li >image9-6       <\/li><li >LRA       <\/li><\/ul><\/div><hr class=\"before-footnotes clear\" \/><div class=\"footnotes\"><ol><li id=\"footnote-225-1\">\"<a href=\"https:\/\/www.flickr.com\/photos\/neofedex\/3446761945\/\" target=\"_blank\" rel=\"noopener noreferrer\">Singulair 10mg<\/a>\" by <a href=\"https:\/\/www.flickr.com\/photos\/neofedex\/\" target=\"_blank\" rel=\"noopener noreferrer\">FedEx<\/a> is licenced under <a href=\"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/2.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">CC BY-NC-ND 2.0<\/a> <a href=\"#return-footnote-225-1\" class=\"return-footnote\" aria-label=\"Return to footnote 1\">&crarr;<\/a><\/li><li id=\"footnote-225-2\">Frandsen, G. &amp; Pennington, S. (2018). <em>Abrams\u2019 clinical drug: Rationales for nursing practice <\/em>(11th ed.). Wolters Kluwer. <a href=\"#return-footnote-225-2\" class=\"return-footnote\" aria-label=\"Return to footnote 2\">&crarr;<\/a><\/li><li id=\"footnote-225-3\">uCentral from Unbound Medicine. <a href=\"https:\/\/www.unboundmedicine.com\/ucentral\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.unboundmedicine.com\/ucentral<\/a> <a href=\"#return-footnote-225-3\" class=\"return-footnote\" aria-label=\"Return to footnote 3\">&crarr;<\/a><\/li><li id=\"footnote-225-4\">This work is a derivative of <a href=\"https:\/\/www.oercommons.org\/authoring\/54330-pharmacology-notes-nursing-implications-for-clinic\/view\" target=\"_blank\" rel=\"noopener noreferrer\">Pharmacology Notes: Nursing Implications for Clinical Practice<\/a> by <a href=\"https:\/\/www.oercommons.org\/profile\/213497\" target=\"_blank\" rel=\"noopener noreferrer\">Gloria Velarde<\/a> licensed under <a href=\"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0\/\" target=\"_blank\" rel=\"noopener noreferrer\">CC BY-NC-SA 4.0<\/a>. <a href=\"#return-footnote-225-4\" class=\"return-footnote\" aria-label=\"Return to footnote 4\">&crarr;<\/a><\/li><li id=\"footnote-225-5\">Frandsen, G. &amp; Pennington, S. (2018). <em>Abrams\u2019 clinical drug: Rationales for nursing practice <\/em>(11th ed.). Wolters Kluwer. <a href=\"#return-footnote-225-5\" class=\"return-footnote\" aria-label=\"Return to footnote 5\">&crarr;<\/a><\/li><li id=\"footnote-225-6\">This work is a derivative of <a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/\" target=\"_blank\" rel=\"noopener noreferrer\">Daily Med<\/a> by <a href=\"https:\/\/www.nlm.nih.gov\/\" target=\"_blank\" rel=\"noopener noreferrer\">U.S. National Library of Medicine<\/a> in the <a href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/\" target=\"_blank\" rel=\"noopener noreferrer\">public domain<\/a>.  <a href=\"#return-footnote-225-6\" class=\"return-footnote\" aria-label=\"Return to footnote 6\">&crarr;<\/a><\/li><li id=\"footnote-225-7\">Adams, M., Holland, N., &amp; Urban, C. (2020). <em>Pharmacology for nurses: A pathophysiologic approach <\/em>(6th ed.)<em>.<\/em> pp. 622-63 &amp; 626. Pearson.  <a href=\"#return-footnote-225-7\" class=\"return-footnote\" aria-label=\"Return to footnote 7\">&crarr;<\/a><\/li><\/ol><\/div>","protected":false},"author":103,"menu_order":13,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":["open-resources-for-nursing-open-rn"],"pb_section_license":""},"chapter-type":[48],"contributor":[68],"license":[],"class_list":["post-225","chapter","type-chapter","status-publish","hentry","chapter-type-numberless","contributor-open-resources-for-nursing-open-rn"],"part":182,"_links":{"self":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/225","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/users\/103"}],"version-history":[{"count":6,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/225\/revisions"}],"predecessor-version":[{"id":2426,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/225\/revisions\/2426"}],"part":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/parts\/182"}],"metadata":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/225\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/media?parent=225"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapter-type?post=225"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/contributor?post=225"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/license?post=225"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}