{"id":292,"date":"2019-11-04T23:42:12","date_gmt":"2019-11-05T04:42:12","guid":{"rendered":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/chapter\/7-1-introduction\/"},"modified":"2022-02-24T16:36:35","modified_gmt":"2022-02-24T21:36:35","slug":"7-1-gastrointestinalintroduction","status":"publish","type":"chapter","link":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/chapter\/7-1-gastrointestinalintroduction\/","title":{"raw":"7.1 Gastrointestinal Elimination Introduction","rendered":"7.1 Gastrointestinal Elimination Introduction"},"content":{"raw":"<div class=\"textbox textbox--examples\"><header class=\"textbox__header\">\r\n<h2>Learning Objectives<\/h2>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n<ol>\r\n \t<li>Identify the classifications and actions of the gastrointestinal system and elimination drugs<\/li>\r\n \t<li>Consider examples of when, how, and to whom gastrointestinal system drugs may be administered<\/li>\r\n \t<li>Identify the side effects and special considerations associated with gastrointestinal system drug therapy<\/li>\r\n \t<li>Identify considerations and implications of using gastrointestinal system medications across the lifespan<\/li>\r\n \t<li>Consider evidence-based concepts when using the nursing process, clinical reasoning, and decision-making related to medications that affect the gastrointestinal system<\/li>\r\n<\/ol>\r\n<\/div>\r\n<\/div>\r\n<div class=\"textbox textbox--exercises\"><header class=\"textbox__header\">\r\n<p class=\"textbox__title\">Key Terms<\/p>\r\n\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n<table class=\"no-lines\" style=\"border-collapse: collapse;width: 100%;height: 379px\" border=\"0\">\r\n<tbody>\r\n<tr style=\"height: 33px\">\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"616\"]adsorption[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"488\"]gastroesophageal reflux disease[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"1848\"]proton pump inhibitor[\/pb_glossary]<\/td>\r\n<\/tr>\r\n<tr style=\"height: 33px\">\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"1847\"]antacids[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"618\"]hematemesis[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"573\"]rebound hyperacidity[\/pb_glossary]<\/td>\r\n<\/tr>\r\n<tr style=\"height: 33px\">\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"615\"]antidiarrheals[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"594\"]hypercalcemia[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"620\"]serotonin syndrome[\/pb_glossary]<\/td>\r\n<\/tr>\r\n<tr style=\"height: 33px\">\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"622\"]antimotility medications[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"623\"]intrinsic factor[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"627\"]stimulants[\/pb_glossary]<\/td>\r\n<\/tr>\r\n<tr style=\"height: 33px\">\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"621\"]area postrema[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"624\"]osmotic agents[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"626\"]stool softeners[\/pb_glossary]<\/td>\r\n<\/tr>\r\n<tr style=\"height: 49px\">\r\n<td style=\"width: 33.3333%;height: 49px\">[pb_glossary id=\"619\"]chemoreceptor trigger zone[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 49px\">[pb_glossary id=\"497\"]Parietal cells[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 49px\">[pb_glossary id=\"576\"]stress-related mucosal damage[\/pb_glossary]<\/td>\r\n<\/tr>\r\n<tr style=\"height: 33px\">\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"1969\"]constipation[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"611\"]pepsin[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"628\"]stress ulcer prophylaxis[\/pb_glossary]<\/td>\r\n<\/tr>\r\n<tr style=\"height: 33px\">\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"612\"]cytochrome P-450 enzymes[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"480\"]peptic ulcer disease[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"609\"]surface epithelium cells[\/pb_glossary]<\/td>\r\n<\/tr>\r\n<tr style=\"height: 33px\">\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"613\"]defecation[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"1853\"]probiotics[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"629\"]THC[\/pb_glossary]<\/td>\r\n<\/tr>\r\n<tr style=\"height: 33px\">\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"614\"]diarrhea[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"625\"]prokinetic[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"579\"]vestibular system[\/pb_glossary]<\/td>\r\n<\/tr>\r\n<tr style=\"height: 33px\">\r\n<td style=\"width: 33.3333%;height: 33px\">[pb_glossary id=\"617\"]gastroenteritis[\/pb_glossary]<\/td>\r\n<td style=\"width: 33.3333%;height: 33px\"><\/td>\r\n<td style=\"width: 33.3333%;height: 33px\"><\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/div>\r\n<\/div>\r\n<span style=\"text-align: initial;font-size: 14pt\">Gastrointestinal complaints are a commonplace occurrence. How many times have you heard someone complaining of an upset stomach, heartburn, nausea, constipation, or diarrhea? Occasionally, these ailments will go away on their own, but if they do not, there are a variety of medications that can be used to treat the disease or symptom. Treatment can involve both the use of prescription and nonprescription drug therapy, in addition to nonpharmacological interventions. In this chapter, you will learn about medications used to treat common disorders within the gastrointestinal system.<\/span>","rendered":"<div class=\"textbox textbox--examples\">\n<header class=\"textbox__header\">\n<h2>Learning Objectives<\/h2>\n<\/header>\n<div class=\"textbox__content\">\n<ol>\n<li>Identify the classifications and actions of the gastrointestinal system and elimination drugs<\/li>\n<li>Consider examples of when, how, and to whom gastrointestinal system drugs may be administered<\/li>\n<li>Identify the side effects and special considerations associated with gastrointestinal system drug therapy<\/li>\n<li>Identify considerations and implications of using gastrointestinal system medications across the lifespan<\/li>\n<li>Consider evidence-based concepts when using the nursing process, clinical reasoning, and decision-making related to medications that affect the gastrointestinal system<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<div class=\"textbox textbox--exercises\">\n<header class=\"textbox__header\">\n<p class=\"textbox__title\">Key Terms<\/p>\n<\/header>\n<div class=\"textbox__content\">\n<table class=\"no-lines\" style=\"border-collapse: collapse;width: 100%;height: 379px\">\n<tbody>\n<tr style=\"height: 33px\">\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_616\">adsorption<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_488\">gastroesophageal reflux disease<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_1848\">proton pump inhibitor<\/a><\/td>\n<\/tr>\n<tr style=\"height: 33px\">\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_1847\">antacids<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_618\">hematemesis<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_573\">rebound hyperacidity<\/a><\/td>\n<\/tr>\n<tr style=\"height: 33px\">\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_615\">antidiarrheals<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_594\">hypercalcemia<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_620\">serotonin syndrome<\/a><\/td>\n<\/tr>\n<tr style=\"height: 33px\">\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_622\">antimotility medications<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_623\">intrinsic factor<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_627\">stimulants<\/a><\/td>\n<\/tr>\n<tr style=\"height: 33px\">\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_621\">area postrema<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_624\">osmotic agents<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_626\">stool softeners<\/a><\/td>\n<\/tr>\n<tr style=\"height: 49px\">\n<td style=\"width: 33.3333%;height: 49px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_619\">chemoreceptor trigger zone<\/a><\/td>\n<td style=\"width: 33.3333%;height: 49px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_497\">Parietal cells<\/a><\/td>\n<td style=\"width: 33.3333%;height: 49px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_576\">stress-related mucosal damage<\/a><\/td>\n<\/tr>\n<tr style=\"height: 33px\">\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_1969\">constipation<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_611\">pepsin<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_628\">stress ulcer prophylaxis<\/a><\/td>\n<\/tr>\n<tr style=\"height: 33px\">\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_612\">cytochrome P-450 enzymes<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_480\">peptic ulcer disease<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_609\">surface epithelium cells<\/a><\/td>\n<\/tr>\n<tr style=\"height: 33px\">\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_613\">defecation<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_1853\">probiotics<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_629\">THC<\/a><\/td>\n<\/tr>\n<tr style=\"height: 33px\">\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_614\">diarrhea<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_625\">prokinetic<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_579\">vestibular system<\/a><\/td>\n<\/tr>\n<tr style=\"height: 33px\">\n<td style=\"width: 33.3333%;height: 33px\"><a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_292_617\">gastroenteritis<\/a><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><\/td>\n<td style=\"width: 33.3333%;height: 33px\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n<p><span style=\"text-align: initial;font-size: 14pt\">Gastrointestinal complaints are a commonplace occurrence. How many times have you heard someone complaining of an upset stomach, heartburn, nausea, constipation, or diarrhea? Occasionally, these ailments will go away on their own, but if they do not, there are a variety of medications that can be used to treat the disease or symptom. Treatment can involve both the use of prescription and nonprescription drug therapy, in addition to nonpharmacological interventions. In this chapter, you will learn about medications used to treat common disorders within the gastrointestinal system.<\/span><\/p>\n<div class=\"glossary\"><span class=\"screen-reader-text\" id=\"definition\">definition<\/span><template id=\"term_292_616\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_616\"><div tabindex=\"-1\"><p>The adhesion of molecules to a surface. For example, bismuth salicylate coats the walls of the GI tract and binds the causative bacteria or toxin for elimination from the GI tract through the stool.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_488\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_488\"><div tabindex=\"-1\"><p>Caused by excessive hydrochloric acid that tends to back up, or reflux, into the lower esophagus.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_1848\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_1848\"><div tabindex=\"-1\"><p>Binds to the hydrogen-potassium ATPase enzyme system of the parietal cell and inhibit the release of hydrogen ions into the stomach.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_1847\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_1847\"><div tabindex=\"-1\"><p>Used to neutralize stomach acid and reduce the symptoms of heartburn.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_618\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_618\"><div tabindex=\"-1\"><p>Blood in the vomit.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_573\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_573\"><div tabindex=\"-1\"><p>A side effect of medication causing elevated levels of hydrochloric acid in the stomach after the medication is discontinued.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_615\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_615\"><div tabindex=\"-1\"><p>Relieve the symptoms of diarrhea, such as an increased frequency and urgency when passing stools, but do not eliminate the cause of it.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_594\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_594\"><div tabindex=\"-1\"><p>Elevated levels of calcium in the bloodstream.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_620\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_620\"><div tabindex=\"-1\"><p>Symptoms associated with serotonin syndrome may include the following combination of signs and symptoms: mental status changes (e.g., agitation, hallucinations, delirium, and coma), autonomic instability (e.g., tachycardia, labile blood pressure, dizziness, diaphoresis, flushing, hyperthermia), neuromuscular symptoms (e.g., tremor, rigidity, myoclonus, hyperreflexia, incoordination), seizures, with or without gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea).<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_622\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_622\"><div tabindex=\"-1\"><p>Medications that help to treat diarrhea by slowing peristalsis.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_623\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_623\"><div tabindex=\"-1\"><p>Necessary for the absorption of vitamin B12 in the small intestine.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_627\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_627\"><div tabindex=\"-1\"><p>Laxatives that cause the intestines to contract, inducing stool to move through the colon.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_621\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_621\"><div tabindex=\"-1\"><p>A structure in the medulla oblongata in the brainstem that controls vomiting. Its location in the brain also allows it to play a vital role in the control of autonomic functions by the central nervous system.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_624\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_624\"><div tabindex=\"-1\"><p>Cause water to be retained with the stool, increasing the number of bowel movements and softening the stool so it is easier to pass.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_626\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_626\"><div tabindex=\"-1\"><p>Laxatives that facilitate movement of water and fats into stool to make it soft and improve regularity of bowel movements.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_619\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_619\"><div tabindex=\"-1\"><p>Area in the brain that responds directly to toxins in the bloodstream and stimulates the vomiting center.\u00a0 The CTZ receives stimuli from several other locations in the body.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_497\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_497\"><div tabindex=\"-1\"><p>cells in the gastric glands that produce and secrete hydrochloric acid (HCl) and intrinsic factor<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_576\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_576\"><div tabindex=\"-1\"><p>A common condition in hospitalized patients that can lead to PUD.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_1969\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_1969\"><div tabindex=\"-1\"><p>Three or fewer bowel movements in a week; stools that are hard, dry or lumpy; stools that are difficult or painful to pass; or the feeling that not all stool has passed.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_611\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_611\"><div tabindex=\"-1\"><p>A digestive enzyme.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_628\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_628\"><div tabindex=\"-1\"><p>Medication to prevent the formation of stress ulcers.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_612\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_612\"><div tabindex=\"-1\"><p>Enzymes produced from the cytochrome P450 genes involved in the formation (synthesis) and breakdown (metabolism) of various molecules, chemicals, and medications within cells.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_480\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_480\"><div tabindex=\"-1\"><p>Occurs when gastric or duodenal ulcers are caused by the breakdown of GI mucosa by pepsin in combination with the caustic effects of hydrochloric acid.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_609\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_609\"><div tabindex=\"-1\"><p>Cells found within the lining of the stomach that secrete mucus as a protective coating.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_613\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_613\"><div tabindex=\"-1\"><p>The digestive process where undigested materials are removed from the body as feces.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_1853\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_1853\"><div tabindex=\"-1\"><p>Used for the prevention and treatment of diarrhea by restoring normal bacteria flora in the gastrointestinal tract.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_629\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_629\"><div tabindex=\"-1\"><p>Tetrahydrocannabinoids found in marijuana.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_614\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_614\"><div tabindex=\"-1\"><p>The passage of three or more loose or liquid stools per day (or more frequent passage than is normal for the individual).<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_625\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_625\"><div tabindex=\"-1\"><p>Medications used to promote peristalsis to empty the gastrointestinal tract and reduce nausea.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_579\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_579\"><div tabindex=\"-1\"><p>An area located within the inner ear that gives a sense of balance and spatial orientation for the purpose of coordinating movement with balance.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_292_617\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_292_617\"><div tabindex=\"-1\"><p>Infection of the intestines.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><\/div>","protected":false},"author":103,"menu_order":1,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":["open-resources-for-nursing-open-rn"],"pb_section_license":""},"chapter-type":[48],"contributor":[68],"license":[],"class_list":["post-292","chapter","type-chapter","status-publish","hentry","chapter-type-numberless","contributor-open-resources-for-nursing-open-rn"],"part":291,"_links":{"self":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/292","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/users\/103"}],"version-history":[{"count":16,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/292\/revisions"}],"predecessor-version":[{"id":2504,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/292\/revisions\/2504"}],"part":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/parts\/291"}],"metadata":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/292\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/media?parent=292"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapter-type?post=292"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/contributor?post=292"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/nursingpharmacology\/wp-json\/wp\/v2\/license?post=292"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}