{"id":1458,"date":"2021-08-25T00:49:45","date_gmt":"2021-08-25T04:49:45","guid":{"rendered":"https:\/\/pressbooks.bccampus.ca\/pathology\/?post_type=chapter&p=1458"},"modified":"2025-01-13T13:07:27","modified_gmt":"2025-01-13T18:07:27","slug":"post-test-for-metastatic-melanoma","status":"publish","type":"chapter","link":"https:\/\/pressbooks.bccampus.ca\/pathology\/chapter\/post-test-for-metastatic-melanoma\/","title":{"raw":"Post-Test for Metastatic Melanoma","rendered":"Post-Test for Metastatic Melanoma"},"content":{"raw":"
[h5p id=\"7\"]<\/div>\r\n
[h5p id=\"21\"]<\/div>\r\n
1. Melanoma can occur in any person, regardless of age, skin tone, and sun exposure.<\/strong>\r\n
    \r\n \t
  • True<\/li>\r\n \t
  • False<\/li>\r\n<\/ul>\r\n2. Metastatic melanoma is lethal.<\/strong>\r\n
      \r\n \t
    • True<\/li>\r\n \t
    • False<\/li>\r\n<\/ul>\r\n3. Where can melanoma begin?<\/strong>\r\n
        \r\n \t
      • Eyes<\/li>\r\n \t
      • Skeletal muscle<\/li>\r\n \t
      • Brain<\/li>\r\n \t
      • Heart<\/li>\r\n<\/ul>\r\n4. Where are common sites of metastases? Select all that apply.\r\n<\/strong>\r\n
          \r\n \t
        • Lungs<\/li>\r\n \t
        • Bone marrow<\/li>\r\n \t
        • Heart<\/li>\r\n \t
        • Liver<\/li>\r\n \t
        • Fat<\/li>\r\n \t
        • Brain<\/li>\r\n \t
        • Nails<\/li>\r\n<\/ul>\r\n5. Fill in the blanks with the following words:<\/strong>\r\n\r\nOlder adults, tumour suppressor genes, DNA damage,\u00a0 young adults\r\n\r\nMelanoma can occur when there is a perfect combination of _____ to _____. Melanoma commonly appears in _____ because of years of accumulated errors in important genes. However, the original damage to DNA occurred when they were _____.\r\n\r\n6. Melanoma that starts in the skin can metastasize to distant sites by:\r\n<\/strong>\r\n\r\nSelect all that apply.<\/strong>\r\n
            \r\n \t
          • Blood flow<\/li>\r\n \t
          • Lymphatic flow<\/li>\r\n \t
          • Exhalation<\/li>\r\n \t
          • Rubbing skin with the melanoma site<\/li>\r\n<\/ul>\r\n7. Refer to Figure 4.6. What do you notice about the cells at the outermost layer (S. corneum) of this section of skin?<\/strong>\r\n\r\n8. Refer to Figure 4.6. What is distinctive about the cells of the stratum spinosum?<\/strong>\r\n\r\n[caption id=\"attachment_885\" align=\"aligncenter\" width=\"523\"]\"\" Figure 4.6[\/caption]\r\n\r\n9. Where is the basement membrane?<\/strong>\r\n
              \r\n \t
            • Between the S. corneum and S. Basale<\/li>\r\n \t
            • At the bottom of the reticular layer of the dermis<\/li>\r\n \t
            • At the junction between the S. basale and papillary layer of the dermis<\/li>\r\n \t
            • At the junction between the papillary and reticular layer of the dermis<\/li>\r\n<\/ul>\r\n
              \r\n

              Answer Key<\/h2>\r\n
                \r\n \t
              1. True<\/li>\r\n \t
              2. True<\/li>\r\n \t
              3. Eyes<\/li>\r\n \t
              4. Lungs, bone marrow, liver, brain<\/li>\r\n \t
              5. DNA damage, tumour suppressor genes, older adults, young adults<\/li>\r\n \t
              6. Blood flow, lymphatic flow<\/li>\r\n \t
              7. These cells do not have nuclei, so you can deduce that they are dead. They appear to be sloughing off.<\/li>\r\n \t
              8. These cells have dehydrated and collapsed, thus giving them their spinay appearance.<\/li>\r\n \t
              9. At the junction between the S. basale and papillary layer of the dermis<\/li>\r\n<\/ol>\r\n<\/div>\r\n<\/div>","rendered":"
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