{"id":990,"date":"2023-01-06T01:42:36","date_gmt":"2023-01-06T06:42:36","guid":{"rendered":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/?post_type=chapter&p=990"},"modified":"2023-01-13T15:22:25","modified_gmt":"2023-01-13T20:22:25","slug":"morbilliform-drug-reaction","status":"publish","type":"chapter","link":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/chapter\/morbilliform-drug-reaction\/","title":{"raw":"Morbilliform Drug Reaction","rendered":"Morbilliform Drug Reaction"},"content":{"raw":"
\r\n

What is it?<\/h1>\r\n<\/div>\r\n
\r\n\r\nMorbilliform drug eruptions, also known as maculopapular or exanthematous drug eruptions, are the most common form of drug eruption and do not cause any serious harm to the patient.\r\n\r\n<\/div>\r\n
\r\n

What causes it?<\/h1>\r\n<\/div>\r\n
\r\n\r\nAntibiotics are the most common causes (especially aminopenicillins, cephalosporins and sulfonamides), but almost any medication can be responsible.\r\n\r\n<\/div>\r\n
\r\n

What does it look like?<\/h1>\r\n<\/div>\r\n
\r\n\r\nThe rash consists of widespread small blanchable erythematous macules and papules appearing 5-14 days after starting the medication. Pruritus is common.\r\n\r\n<\/div>\r\n
\r\n

How is it diagnosed?<\/h1>\r\n<\/div>\r\n
\r\n\r\nMorbilliform drug rash is diagnosed clinically. Drug history should include any topical, over-the-counter, and natural health products the patient has been using. It might not be possible to definitively differentiate a morbilliform drug reaction from a viral exanthem or to know with certainty which medication was the culprit.\r\n\r\n<\/div>\r\n
\r\n

How is it treated?<\/h1>\r\nOnce the responsible medication is stopped, the rash typically resolves in 7-14 days. However, if a medication is considered necessary, you can \u201ctreat through\u201d the rash as morbilliform drug eruptions are not life threatening. Topical corticosteroids and\/or oral antihistamines are helpful for control of associated itch.\r\n\r\n \r\n\r\n[caption id=\"attachment_1002\" align=\"aligncenter\" width=\"300\"]\"\" Image 11.1: Morbilliform eruption demonstrating diffuse blachable macules and papules[\/caption]\r\n\r\n<\/div>","rendered":"
\n

What is it?<\/h1>\n<\/div>\n
\n

Morbilliform drug eruptions, also known as maculopapular or exanthematous drug eruptions, are the most common form of drug eruption and do not cause any serious harm to the patient.<\/p>\n<\/div>\n

\n

What causes it?<\/h1>\n<\/div>\n
\n

Antibiotics are the most common causes (especially aminopenicillins, cephalosporins and sulfonamides), but almost any medication can be responsible.<\/p>\n<\/div>\n

\n

What does it look like?<\/h1>\n<\/div>\n
\n

The rash consists of widespread small blanchable erythematous macules and papules appearing 5-14 days after starting the medication. Pruritus is common.<\/p>\n<\/div>\n

\n

How is it diagnosed?<\/h1>\n<\/div>\n
\n

Morbilliform drug rash is diagnosed clinically. Drug history should include any topical, over-the-counter, and natural health products the patient has been using. It might not be possible to definitively differentiate a morbilliform drug reaction from a viral exanthem or to know with certainty which medication was the culprit.<\/p>\n<\/div>\n

\n

How is it treated?<\/h1>\n

Once the responsible medication is stopped, the rash typically resolves in 7-14 days. However, if a medication is considered necessary, you can \u201ctreat through\u201d the rash as morbilliform drug eruptions are not life threatening. Topical corticosteroids and\/or oral antihistamines are helpful for control of associated itch.<\/p>\n

 <\/p>\n

\"\"
Image 11.1: Morbilliform eruption demonstrating diffuse blachable macules and papules<\/figcaption><\/figure>\n<\/div>\n","protected":false},"author":1682,"menu_order":2,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[],"contributor":[],"license":[],"class_list":["post-990","chapter","type-chapter","status-publish","hentry"],"part":986,"_links":{"self":[{"href":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/wp-json\/pressbooks\/v2\/chapters\/990","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/wp-json\/wp\/v2\/users\/1682"}],"version-history":[{"count":3,"href":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/wp-json\/pressbooks\/v2\/chapters\/990\/revisions"}],"predecessor-version":[{"id":1437,"href":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/wp-json\/pressbooks\/v2\/chapters\/990\/revisions\/1437"}],"part":[{"href":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/wp-json\/pressbooks\/v2\/parts\/986"}],"metadata":[{"href":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/wp-json\/pressbooks\/v2\/chapters\/990\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/wp-json\/wp\/v2\/media?parent=990"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/wp-json\/pressbooks\/v2\/chapter-type?post=990"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/wp-json\/wp\/v2\/contributor?post=990"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/pedsdermprimer\/wp-json\/wp\/v2\/license?post=990"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}