Substance Use Disorders
What is a Substance Use Disorder?
A substance use disorder (SUD) is defined as a mental disorder that leads to a person not being able to control their use of substances such as legal or illegal drugs, alcohol, or medications.[1] While risk factors for SUD and addiction include genetics, environment and life experiences, chronic stress is a very real risk factor.[2] There is a reciprocal relationship between stress and addiction. Some people resort to using drugs or alcohol to manage their stress, and reciprocally, the impact that substance misuse has on a person’s life, health and relationships may cause stress.[3]
Prolonged use of alcohol or drugs has been shown to be correlated with changes in areas of the brain that are responsible for impulse control, motivation, pleasure and behavior – making it very difficult for people to stop using substances despite negative consequences.[4] Likewise, chronic stress impacts the neurotransmitters dopamine (chemical that allows you to feel good/happy) and serotonin (helps keep your mood balanced), and the hormone melatonin (helps regulate your sleep), leading to negative consequences in mood and sleep.[5][6] Using a substance to help your mood by giving you a quick high is only temporary relief that doesn’t consider the damage being caused by stress or substance use.
In Canada, it is estimated that approximately 21% of the population will meet the criteria for addiction in their lifetime.[7] The following table illustrates that Canadian alcohol use is by far the top used substance.
The next chapters will review alcohol and drug use disorders individually.
Media Attributions
- Figure 20.1 Spectrum of Substance Use adapted by Jody Vaughan is licensed under a CC BY-SA (Attribution ShareAlike) license
- Table 20.1 Substance Use 2017 adapted by Jody Vaughan is licensed under a CC BY-SA (Attribution ShareAlike) license
- National Institute of Mental Health. (2021). Substance use and co-occurring disorders. Retrieved from: https://www.nimh.nih.gov/health/topics/substance-use-and-mental-health ↵
- National Institute on Drug Abuse. (2020). Drugs, brains, and behavior: The science of addiction. Retrieved from: https://nida.nih.gov/publications/drugs-brains-behavior-science-addiction/drug-misuse-addiction ↵
- National Institute of Mental Health. (2021). Substance use and co-occurring disorders. Retrieved from: https://www.nimh.nih.gov/health/topics/substance-use-and-mental-health ↵
- National Institute on Drug Abuse. (2021). Principles of drug addiction treatment: A research-based guide (3rd ed.) Retrieved from: https://nida.nih.gov/publications/principles-drug-addiction-treatment-research-based-guide-third-edition/preface ↵
- Natarajan, R., Forrester, L., Chiaia, N., and Yamamoto, B. (2017). Chronic-Stress-Induced Behavioral Changes Associated with Subregion-Selective Serotonin Cell Death in the Dorsal Raphe. Journal of Neuroscience 28 June 2017, 37 (26) 6214-6223. Retrieved from: https://www.jneurosci.org/content/37/26/6214 ↵
- Bloomfield, M., McCutcheon, R., Kempton, M., Freeman, T., Howes, O. (2019). The effects of psychosocial stress on dopaminergic function and the acute stress response. eLife 8:e46797. Retrieved from: https://elifesciences.org/articles/46797 ↵
- Statistics Canada. (2015). Mental Health and Substance Use Disorders in Canada. Retrieved from: http://www.statcan.gc.ca/pub/82-624-x/2013001/article/11855-eng.htm ↵