{"id":88,"date":"2021-05-22T22:31:40","date_gmt":"2021-05-23T02:31:40","guid":{"rendered":"https:\/\/pressbooks.bccampus.ca\/rickyturgeon\/?post_type=chapter&p=88"},"modified":"2022-01-12T22:57:18","modified_gmt":"2022-01-13T03:57:18","slug":"composite-outcome-was-the-primary-outcome-a-combination-of-outcomes","status":"publish","type":"chapter","link":"https:\/\/pressbooks.bccampus.ca\/rickyturgeon\/chapter\/composite-outcome-was-the-primary-outcome-a-combination-of-outcomes\/","title":{"raw":"Composite outcome: Was the primary outcome a combination of outcomes?","rendered":"Composite outcome: Was the primary outcome a combination of outcomes?"},"content":{"raw":"By combining several individual outcomes into a [pb_glossary id=\"359\"]composite outcome[\/pb_glossary] a trial can increase its ability to detect a difference between groups. However, [pb_glossary id=\"359\"]composite outcomes[\/pb_glossary] require careful interpretation of the individual components to avoid making erroneous conclusions.\r\n
Checklist Questions<\/h1>\r\n
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Are the components of the [pb_glossary id=\"359\"]composite outcome[\/pb_glossary] all of similar importance to patients?<\/td>\r\n<\/tr>\r\n
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Did the components occur with similar frequencies?<\/td>\r\n<\/tr>\r\n
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Are the point estimates of treatment effect ([pb_glossary id=\"110\"]HR[\/pb_glossary], [pb_glossary id=\"103\"]OR[\/pb_glossary], [pb_glossary id=\"109\"]RR[\/pb_glossary]) similar between each component? Do the 95% CIs<\/a> overlap? Are they sufficiently narrow?<\/td>\r\n<\/tr>\r\n