{"id":696,"date":"2023-10-26T11:26:30","date_gmt":"2023-10-26T15:26:30","guid":{"rendered":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/chapter\/acute-coronary-syndrome\/"},"modified":"2023-11-10T16:39:18","modified_gmt":"2023-11-10T21:39:18","slug":"acute-coronary-syndrome","status":"publish","type":"chapter","link":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/chapter\/acute-coronary-syndrome\/","title":{"raw":"Acute Coronary Syndrome","rendered":"Acute Coronary Syndrome"},"content":{"raw":"<div class=\"textbox textbox--exercises\">\r\n<div class=\"textbox__content\">In this chapter,\u00a0you will find Canadian guidelines for the acute management of patients presenting with a STEMI\/NSTEMI and recommended drug therapy long term. The majority of resources provided are related to dual antiplatelet therapy and optimal duration of therapy for specific patients.<\/div>\r\n<\/div>\r\n<h2>Student Resources<\/h2>\r\n<a href=\"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-content\/uploads\/sites\/1956\/2023\/07\/Acute-Coronary-Syndrome-One-Pager-1-1.pdf\">Acute Coronary Syndrome One Pager<\/a>\r\n\r\n<a href=\"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-content\/uploads\/sites\/1956\/2023\/07\/Summary-CAD-drug-tables.pdf\">CAD Drug Tables<\/a>\r\n<h1>Tools<\/h1>\r\n<details><summary><span style=\"color: #000000\"><em>DAPT Score<\/em><\/span><\/summary>\r\n<table class=\"grid\" style=\"border-collapse: collapse;width: 100%;height: 75px\" border=\"0\">\r\n<tbody>\r\n<tr>\r\n<td style=\"width: 18.9993%\"><strong>Purpose<\/strong><\/td>\r\n<td style=\"width: 80.9282%\">Assess risk of thromboembolic events to determine if patients would benefit from extended DAPT.<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 18.9993%\"><strong>Type of Resource<\/strong><\/td>\r\n<td style=\"width: 80.9282%\">Scoring tool<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 18.9993%\"><strong>Included<\/strong><\/td>\r\n<td style=\"width: 80.9282%\">Tool consists of risk factors associated with increased risk of thromboembolic events.\r\n\r\nInterpretation of results:\r\n<ul>\r\n \t<li>-2 to 1: extended DAPT not recommended<\/li>\r\n \t<li>2+: Extended DAPT recommended<\/li>\r\n<\/ul>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 18.9993%\"><strong>Student Bottom Line<\/strong><\/td>\r\n<td style=\"width: 80.9282%\">In all patients with a PCI who have received DAPT for 1 year, we recommend using this scoring tool to determine if patients should discontinue DAPT and continue on single anti platelet therapy or extend DAPT for up to 3 years.<\/td>\r\n<\/tr>\r\n<tr class=\"shaded\" style=\"height: 15px\">\r\n<td style=\"text-align: center;height: 15px;width: 99.9275%\" colspan=\"2\"><a href=\"https:\/\/www.mdcalc.com\/calc\/10016\/dual-antiplatelet-therapy-dapt-score\">VIEW RESOURCE<\/a><\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/details><details><summary><span style=\"color: #000000\"><em>Thrombolysis in Myocardial Infarction Score (TIMI)<\/em><\/span><\/summary>\r\n<table class=\"grid\" style=\"border-collapse: collapse;width: 100%;height: 148px\" border=\"0\">\r\n<tbody>\r\n<tr>\r\n<td style=\"width: 11.7476%\"><strong>Purpose<\/strong><\/td>\r\n<td>Assess patients risk of mortality, recurrent MI or ischemia in the next 14 days in patients with unstable angina or NSTEMI [pb_glossary id=\"55\"]unstable angina[\/pb_glossary].<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 11.7476%\"><strong>Type of Resource<\/strong><\/td>\r\n<td style=\"width: 88.1798%\">Scoring tool<\/td>\r\n<\/tr>\r\n<tr style=\"height: 88px\">\r\n<td style=\"width: 11.7476%\"><strong>Included<\/strong><\/td>\r\n<td style=\"width: 88.1798%\">Tool consists of risk factors associated with mortality.\r\n\r\nInterpretation of results:\r\n<ul>\r\n \t<li>0 to 1: 5%<\/li>\r\n \t<li>2: 8%<\/li>\r\n \t<li>3: 13%<\/li>\r\n \t<li>4: 20%<\/li>\r\n \t<li>5: 26%<\/li>\r\n \t<li>6-7: 41%<\/li>\r\n<\/ul>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td style=\"width: 11.7476%\"><strong>Student Bottom Line<\/strong><\/td>\r\n<td style=\"width: 88.1798%\">In patients with unstable angina or an NSTEMI, use this scoring tool to determine your patients risk of mortality or recurrent cardiovascular event.<\/td>\r\n<\/tr>\r\n<tr class=\"shaded\" style=\"height: 15px\">\r\n<td style=\"text-align: center;height: 15px;width: 99.9275%\" colspan=\"2\"><a href=\"https:\/\/www.mdcalc.com\/calc\/111\/timi-risk-score-ua-nstemi\">VIEW RESOURCE<\/a><strong>\r\n<\/strong><\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/details>\r\n<h1>Guidelines<\/h1>\r\n<details><summary><span style=\"color: #000000\"><em>The Canadian Cardiovascular Society Guidelines<\/em><\/span><\/summary>\r\n<table class=\"grid\" style=\"border-collapse: collapse;width: 100%;height: 60px\" border=\"0\">\r\n<tbody>\r\n<tr>\r\n<td><strong>Purpose<\/strong><\/td>\r\n<td>Guide treatment recommendations for patients presenting with acute STEMI.<\/td>\r\n<\/tr>\r\n<tr>\r\n<td><strong>Type of Resource<\/strong><\/td>\r\n<td>Guideline<\/td>\r\n<\/tr>\r\n<tr>\r\n<td><strong>Included<\/strong><\/td>\r\n<td>\r\n<ol>\r\n \t<li>PCI vs fibrinolytic considerations<\/li>\r\n \t<li>Drug therapy recommendations in acute setting<\/li>\r\n<\/ol>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td><strong>Student Bottom Line<\/strong><\/td>\r\n<td>These detailed guidelines are a great source of information to review acute treatment management in patients with a myocardial infarction.<\/td>\r\n<\/tr>\r\n<tr class=\"shaded\">\r\n<td style=\"text-align: center\" colspan=\"2\"><a href=\"https:\/\/www.onlinecjc.ca\/article\/S0828-282X(18)31321-7\/pdf\">VIEW RESOURCE<\/a><\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/details><details><summary><span style=\"color: #000000\"><em>The Canadian Cardiovascular Society \u2192 Duration of DAPT<\/em><\/span><\/summary>\r\n<table class=\"grid\" style=\"border-collapse: collapse;width: 100%;height: 148px\" border=\"0\">\r\n<tbody>\r\n<tr style=\"height: 15px\">\r\n<td style=\"height: 15px\"><strong>Purpose<\/strong><\/td>\r\n<td style=\"height: 15px\">Guide treatment recommendations for duration of DAPT in patients who undergo PCI.<\/td>\r\n<\/tr>\r\n<tr style=\"height: 15px\">\r\n<td style=\"height: 15px\"><strong>Type of Resource<\/strong><\/td>\r\n<td style=\"height: 15px\">Guideline<\/td>\r\n<\/tr>\r\n<tr style=\"height: 72px\">\r\n<td style=\"height: 72px\"><strong>Included<\/strong><\/td>\r\n<td style=\"height: 72px\">\r\n<ol>\r\n \t<li>Duration of DAPT therapy based on individual characteristics<\/li>\r\n \t<li>Clinical features which place patients at high risk of thromboembolic events (extended DAPT recommended)<\/li>\r\n \t<li>Factors associated with increased bleeding risk (shorted DAPT recommended)<\/li>\r\n \t<li>Practical tips for the clinical setting<\/li>\r\n<\/ol>\r\n<\/td>\r\n<\/tr>\r\n<tr style=\"height: 31px\">\r\n<td style=\"height: 31px\"><strong>Student Bottom Line<\/strong><\/td>\r\n<td style=\"height: 31px\">In all patients with a PCI, this is a great tool to assess the optimal duration of DAPT therapy in your individual patient.<\/td>\r\n<\/tr>\r\n<tr class=\"shaded\" style=\"height: 15px\">\r\n<td style=\"text-align: center;height: 15px\" colspan=\"2\"><a href=\"https:\/\/onlinecjc.ca\/article\/S0828-282X(23)01841-X\/fulltext\">VIEW RESOURCE (full guidelines)<\/a> - <a href=\"https:\/\/ccs.ca\/app\/uploads\/2020\/11\/APT_Gui_2018_PG_EN_web.pdf\">VIEW RESOURCE (pocket guidelines)<\/a><\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/details><details><summary><span style=\"color: #000000\"><em>Post MI Care<\/em><\/span><\/summary>\r\n<table class=\"grid\" style=\"border-collapse: collapse;width: 100%;height: 75px\" border=\"0\">\r\n<tbody>\r\n<tr>\r\n<td><strong>Purpose<\/strong><\/td>\r\n<td>Guide treatment recommendations for long term management in patients post-MI.<\/td>\r\n<\/tr>\r\n<tr>\r\n<td><strong>Type of Resource<\/strong><\/td>\r\n<td>Summary of trials and recommended drug therapy post MI<\/td>\r\n<\/tr>\r\n<tr>\r\n<td><strong>Included<\/strong><\/td>\r\n<td>\r\n<ol>\r\n \t<li>Indications for drug therapy<\/li>\r\n \t<li>Recommended dosages<\/li>\r\n \t<li>Contraindications for drug therapy<\/li>\r\n \t<li>Benefits patients may receive from the drug therapy<\/li>\r\n<\/ol>\r\n<\/td>\r\n<\/tr>\r\n<tr>\r\n<td><strong>Student Bottom Line<\/strong><\/td>\r\n<td>A great tool with a summary of drug therapy recommended for patients with a history of MI.<\/td>\r\n<\/tr>\r\n<tr class=\"shaded\" style=\"height: 15px\">\r\n<td style=\"text-align: center;height: 15px\" colspan=\"2\"><a href=\"https:\/\/www.cardioguide.ca\/post-mi-care\/\">VIEW RESOURCE<\/a><\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/details>","rendered":"<div class=\"textbox textbox--exercises\">\n<div class=\"textbox__content\">In this chapter,\u00a0you will find Canadian guidelines for the acute management of patients presenting with a STEMI\/NSTEMI and recommended drug therapy long term. The majority of resources provided are related to dual antiplatelet therapy and optimal duration of therapy for specific patients.<\/div>\n<\/div>\n<h2>Student Resources<\/h2>\n<p><a href=\"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-content\/uploads\/sites\/1956\/2023\/07\/Acute-Coronary-Syndrome-One-Pager-1-1.pdf\">Acute Coronary Syndrome One Pager<\/a><\/p>\n<p><a href=\"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-content\/uploads\/sites\/1956\/2023\/07\/Summary-CAD-drug-tables.pdf\">CAD Drug Tables<\/a><\/p>\n<h1>Tools<\/h1>\n<details>\n<summary><span style=\"color: #000000\"><em>DAPT Score<\/em><\/span><\/summary>\n<table class=\"grid\" style=\"border-collapse: collapse;width: 100%;height: 75px\">\n<tbody>\n<tr>\n<td style=\"width: 18.9993%\"><strong>Purpose<\/strong><\/td>\n<td style=\"width: 80.9282%\">Assess risk of thromboembolic events to determine if patients would benefit from extended DAPT.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 18.9993%\"><strong>Type of Resource<\/strong><\/td>\n<td style=\"width: 80.9282%\">Scoring tool<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 18.9993%\"><strong>Included<\/strong><\/td>\n<td style=\"width: 80.9282%\">Tool consists of risk factors associated with increased risk of thromboembolic events.<\/p>\n<p>Interpretation of results:<\/p>\n<ul>\n<li>-2 to 1: extended DAPT not recommended<\/li>\n<li>2+: Extended DAPT recommended<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 18.9993%\"><strong>Student Bottom Line<\/strong><\/td>\n<td style=\"width: 80.9282%\">In all patients with a PCI who have received DAPT for 1 year, we recommend using this scoring tool to determine if patients should discontinue DAPT and continue on single anti platelet therapy or extend DAPT for up to 3 years.<\/td>\n<\/tr>\n<tr class=\"shaded\" style=\"height: 15px\">\n<td style=\"text-align: center;height: 15px;width: 99.9275%\" colspan=\"2\"><a href=\"https:\/\/www.mdcalc.com\/calc\/10016\/dual-antiplatelet-therapy-dapt-score\">VIEW RESOURCE<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/details>\n<details>\n<summary><span style=\"color: #000000\"><em>Thrombolysis in Myocardial Infarction Score (TIMI)<\/em><\/span><\/summary>\n<table class=\"grid\" style=\"border-collapse: collapse;width: 100%;height: 148px\">\n<tbody>\n<tr>\n<td style=\"width: 11.7476%\"><strong>Purpose<\/strong><\/td>\n<td>Assess patients risk of mortality, recurrent MI or ischemia in the next 14 days in patients with unstable angina or NSTEMI unstable angina.<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 11.7476%\"><strong>Type of Resource<\/strong><\/td>\n<td style=\"width: 88.1798%\">Scoring tool<\/td>\n<\/tr>\n<tr style=\"height: 88px\">\n<td style=\"width: 11.7476%\"><strong>Included<\/strong><\/td>\n<td style=\"width: 88.1798%\">Tool consists of risk factors associated with mortality.<\/p>\n<p>Interpretation of results:<\/p>\n<ul>\n<li>0 to 1: 5%<\/li>\n<li>2: 8%<\/li>\n<li>3: 13%<\/li>\n<li>4: 20%<\/li>\n<li>5: 26%<\/li>\n<li>6-7: 41%<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 11.7476%\"><strong>Student Bottom Line<\/strong><\/td>\n<td style=\"width: 88.1798%\">In patients with unstable angina or an NSTEMI, use this scoring tool to determine your patients risk of mortality or recurrent cardiovascular event.<\/td>\n<\/tr>\n<tr class=\"shaded\" style=\"height: 15px\">\n<td style=\"text-align: center;height: 15px;width: 99.9275%\" colspan=\"2\"><a href=\"https:\/\/www.mdcalc.com\/calc\/111\/timi-risk-score-ua-nstemi\">VIEW RESOURCE<\/a><strong><br \/>\n<\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/details>\n<h1>Guidelines<\/h1>\n<details>\n<summary><span style=\"color: #000000\"><em>The Canadian Cardiovascular Society Guidelines<\/em><\/span><\/summary>\n<table class=\"grid\" style=\"border-collapse: collapse;width: 100%;height: 60px\">\n<tbody>\n<tr>\n<td><strong>Purpose<\/strong><\/td>\n<td>Guide treatment recommendations for patients presenting with acute STEMI.<\/td>\n<\/tr>\n<tr>\n<td><strong>Type of Resource<\/strong><\/td>\n<td>Guideline<\/td>\n<\/tr>\n<tr>\n<td><strong>Included<\/strong><\/td>\n<td>\n<ol>\n<li>PCI vs fibrinolytic considerations<\/li>\n<li>Drug therapy recommendations in acute setting<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<tr>\n<td><strong>Student Bottom Line<\/strong><\/td>\n<td>These detailed guidelines are a great source of information to review acute treatment management in patients with a myocardial infarction.<\/td>\n<\/tr>\n<tr class=\"shaded\">\n<td style=\"text-align: center\" colspan=\"2\"><a href=\"https:\/\/www.onlinecjc.ca\/article\/S0828-282X(18)31321-7\/pdf\">VIEW RESOURCE<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/details>\n<details>\n<summary><span style=\"color: #000000\"><em>The Canadian Cardiovascular Society \u2192 Duration of DAPT<\/em><\/span><\/summary>\n<table class=\"grid\" style=\"border-collapse: collapse;width: 100%;height: 148px\">\n<tbody>\n<tr style=\"height: 15px\">\n<td style=\"height: 15px\"><strong>Purpose<\/strong><\/td>\n<td style=\"height: 15px\">Guide treatment recommendations for duration of DAPT in patients who undergo PCI.<\/td>\n<\/tr>\n<tr style=\"height: 15px\">\n<td style=\"height: 15px\"><strong>Type of Resource<\/strong><\/td>\n<td style=\"height: 15px\">Guideline<\/td>\n<\/tr>\n<tr style=\"height: 72px\">\n<td style=\"height: 72px\"><strong>Included<\/strong><\/td>\n<td style=\"height: 72px\">\n<ol>\n<li>Duration of DAPT therapy based on individual characteristics<\/li>\n<li>Clinical features which place patients at high risk of thromboembolic events (extended DAPT recommended)<\/li>\n<li>Factors associated with increased bleeding risk (shorted DAPT recommended)<\/li>\n<li>Practical tips for the clinical setting<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<tr style=\"height: 31px\">\n<td style=\"height: 31px\"><strong>Student Bottom Line<\/strong><\/td>\n<td style=\"height: 31px\">In all patients with a PCI, this is a great tool to assess the optimal duration of DAPT therapy in your individual patient.<\/td>\n<\/tr>\n<tr class=\"shaded\" style=\"height: 15px\">\n<td style=\"text-align: center;height: 15px\" colspan=\"2\"><a href=\"https:\/\/onlinecjc.ca\/article\/S0828-282X(23)01841-X\/fulltext\">VIEW RESOURCE (full guidelines)<\/a> &#8211; <a href=\"https:\/\/ccs.ca\/app\/uploads\/2020\/11\/APT_Gui_2018_PG_EN_web.pdf\">VIEW RESOURCE (pocket guidelines)<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/details>\n<details>\n<summary><span style=\"color: #000000\"><em>Post MI Care<\/em><\/span><\/summary>\n<table class=\"grid\" style=\"border-collapse: collapse;width: 100%;height: 75px\">\n<tbody>\n<tr>\n<td><strong>Purpose<\/strong><\/td>\n<td>Guide treatment recommendations for long term management in patients post-MI.<\/td>\n<\/tr>\n<tr>\n<td><strong>Type of Resource<\/strong><\/td>\n<td>Summary of trials and recommended drug therapy post MI<\/td>\n<\/tr>\n<tr>\n<td><strong>Included<\/strong><\/td>\n<td>\n<ol>\n<li>Indications for drug therapy<\/li>\n<li>Recommended dosages<\/li>\n<li>Contraindications for drug therapy<\/li>\n<li>Benefits patients may receive from the drug therapy<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n<tr>\n<td><strong>Student Bottom Line<\/strong><\/td>\n<td>A great tool with a summary of drug therapy recommended for patients with a history of MI.<\/td>\n<\/tr>\n<tr class=\"shaded\" style=\"height: 15px\">\n<td style=\"text-align: center;height: 15px\" colspan=\"2\"><a href=\"https:\/\/www.cardioguide.ca\/post-mi-care\/\">VIEW RESOURCE<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/details>\n<div class=\"glossary\"><span class=\"screen-reader-text\" id=\"definition\">definition<\/span><template id=\"term_696_55\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_696_55\"><div tabindex=\"-1\"><\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><\/div>","protected":false},"author":1076,"menu_order":1,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":"cc-by"},"chapter-type":[],"contributor":[68],"license":[53],"class_list":["post-696","chapter","type-chapter","status-publish","hentry","contributor-oliviabailey-6mh4r9hycn","license-cc-by"],"part":694,"_links":{"self":[{"href":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-json\/pressbooks\/v2\/chapters\/696","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-json\/wp\/v2\/users\/1076"}],"version-history":[{"count":3,"href":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-json\/pressbooks\/v2\/chapters\/696\/revisions"}],"predecessor-version":[{"id":752,"href":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-json\/pressbooks\/v2\/chapters\/696\/revisions\/752"}],"part":[{"href":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-json\/pressbooks\/v2\/parts\/694"}],"metadata":[{"href":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-json\/pressbooks\/v2\/chapters\/696\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-json\/wp\/v2\/media?parent=696"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-json\/pressbooks\/v2\/chapter-type?post=696"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-json\/wp\/v2\/contributor?post=696"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/pressbooks.bccampus.ca\/rxpidresources\/wp-json\/wp\/v2\/license?post=696"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}