Hepatic Module
Reading Outcomes
At the end of class on March 04, 2020, you should be able to:
- Explain the normal physiological role and functions of liver
- Outline the transport of bile and state three main functions of bile.
- Outline the normal transportation, processing and elimination of bilirubin.
- Explain the utility of 10 common clinical tests associated with liver function (e.g., what information does it provide? when might the test result be abnormal?):
- serum (total) bilirubin
- serum unconjugated bilirubin
- urobilinogen
- aspartate aminotransferase (AST)
- alanine aminotransferase (ALT)
- alkaline phosphatase (ALP)
- gamma-glutamyltransferase (GGT)
- prothrombin time
- international normalized ration (INR)
- reticulocyte count
- Briefly describe the causes, pathophysiology and symptoms of the following common disorders and how they relate to jandice (pre-hepatic, hepatic, post-hepatic subtypes):
- hemolytic anemia,
- Gilbert syndrome,
- Dubin-Johnson syndrome,
- hepatitis,
- cirrhosis,
- post-hepatic obstruction
- Given a case study, defend the most probable diagnosis with physiological explanations of the clinical findings and laboratory test results
Please note that this reading resource alone may NOT address all of the listed module reading outcomes above. Additional research and independent learning may be necessary to fully prepare for class.
