Other Inflammatory Conditions

Erythema multiforme is a self-limiting hypersensitivity reaction that is most often triggered by herpes simplex virus. It classically presents with “target” lesions consisting of 3 concentric zones: a dusky centre that blisters or crusts, a pale pink middle layer and a red outer ring. Lesions commonly begin on the hands and feet but may become widespread and involve the lips and mouth.

Sweet syndrome is an inflammatory disorder that presents with painful red, edematous papules and nodules. Patients often have fevers malaise and elevated white blood cells.  Sweet syndrome may be caused by a wide variety of triggers including infections, autoimmune conditions, drugs and malignancies (especially hematologic).