Cephalexin

Used commonly for impetigo, folliculitis, and secondary infections of other dermatologic conditions. Side effects include GI upset and drug hypersensitivity.

Doxycycline/Tetracycline/Minocycline

Used commonly for acne vulgaris, rosacea and periorificial dermatitis. Side effects include GI upset, reflux and photosensitivity. To decrease GI upset tetracyclines should be taken when upright, not right before bed, and with plenty of water. Prolonged use of tetracycline antibiotics should be avoided in children younger than 8 years old due to risk of dental staining, but they can be used safely in all ages for up to 3 weeks if necessary for treatment of infections (ex. Rocky Mountain Spotted Fever). A potential side effect of prolonged use of minocycline is skin hyperpigmentation. All of the tetracyclines have a possible risk of drug hypersensitivity, and minocycline can cause an autoimmune lupus-like reaction.

Trimethoprim-sulfamethoxazole

Useful for resistant acne vulgaris or skin infections. Side effects include GI upset and drug hypersensitivity.