Systemic Therapies: Cyclosporine 

Cyclosporine is used for severe psoriasis or atopic dermatitis, and sometimes in severe adverse drug reactions. Possible side effects include renal dysfunction, hypertension, headache, hyperkalemia, hyperuricemia, hypomagnesemia, hyperlipidemia and immune compromise. Baseline laboratory monitoring is CBC, BUN, creatinine, electrolytes (including Mg), uric acid, liver function tests and fasting lipids. Blood pressure should be checked. Follow-up labs for CBC diff, BUN, creatinine and ALT are done monthly, and blood pressure is checked at each follow-up visit. Live vaccines should not be given to patients taking cyclosporine. Due to side effects, the duration of cyclosporin use should be limited.