Metastatic Cancer – Melanoma

Post-Test for Metastatic Melanoma

Jennifer Kong

1. Melanoma can occur in any person, regardless of age, skin tone, and sun exposure.

  • True
  • False

2. Metastatic melanoma is lethal.

  • True
  • False

3. Where can melanoma begin?

  • Eyes
  • Skeletal muscle
  • Brain
  • Heart

4. Where are common sites of metastases? Select all that apply.

  • Lungs
  • Bone marrow
  • Heart
  • Liver
  • Fat
  • Brain
  • Nails

5. Fill in the blanks with the following words:

Older adults, tumour suppressor genes, DNA damage,  young adults

Melanoma can occur when there is a perfect combination of _____ to _____. Melanoma commonly appears in _____ because of years of accumulated errors in important genes. However, the original damage to DNA occurred when they were _____.

6. Melanoma that starts in the skin can metastasize to distant sites by:

Select all that apply.

  • Blood flow
  • Lymphatic flow
  • Exhalation
  • Rubbing skin with the melanoma site

7. Refer to Figure 4.6. What do you notice about the cells at the outermost layer (S. corneum) of this section of skin?

8. Refer to Figure 4.6. What is distinctive about the cells of the stratum spinosum?

Figure 4.6

9. Where is the basement membrane?

  • Between the S. corneum and S. Basale
  • At the bottom of the reticular layer of the dermis
  • At the junction between the S. basale and papillary layer of the dermis
  • At the junction between the papillary and reticular layer of the dermis

Answer Key

  1. True
  2. True
  3. Eyes
  4. Lungs, bone marrow, liver, brain
  5. DNA damage, tumour suppressor genes, older adults, young adults
  6. Blood flow, lymphatic flow
  7. These cells do not have nuclei, so you can deduce that they are dead. They appear to be sloughing off.
  8. These cells have dehydrated and collapsed, thus giving them their spinay appearance.
  9. At the junction between the S. basale and papillary layer of the dermis

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Pathology Copyright © 2022 by Jennifer Kong is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, except where otherwise noted.

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