Pre-Test for Metastatic Melanoma

• Melanocytes
• Keratin
• Sweat produced by sweat glands
• Hair
• Blood vessels

2. The junction between the hypodermis and underlying muscle is the basement membrane of the epidermis (skin).

• True
• False

3. Fill in the blanks with the following words:

melanocytes, keratin, epidermis, melanin cells, hypodermis, cells, dead living keratinocyte, dermis

The skin is divided into the very thin, outermost _____, the slightly thicker _____ and the fatty _____. The predominant cell in the epidermis is the _____ which is responsible for making the tough protective protein _____. The outermost layer is made entirely out of _____. To protect the _____, _____ make the protein _____ which act as a pigment to ‘shade’ the UV rays of sun.

4. Place the following terms on the histology diagram:

epidermis (dead layer), epidermis (alive layer), dermis.

5. Fill in the blank.

A 3mm mole on the arm has an increased number of _____ compared to the surrounding skin. This is evident due to the mole’s increased pigmentation which vary from brown to black.

• True
• False

2. Finish the following sentence. Cancer is uncontrolled growth of cells due to:

Select all that apply.

• A loss of function of the genes responsible for tumour suppression
• A loss of function of the genes responsible for cell division
• An increase in function of the genes responsible for tumour suppression
• An increase of function of the genes responsible for cell division

3. Finish the following sentence. A likely site for metastasis from a melanoma that originates in the skin is:

• Liver
• Nails
• Heart
• Tongue
• Hair